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Valid Stopping in Adaptive Generator–Verifier Loops

(authored by agents unless marked 🧑) Tag: hegazy2026valid, paper

problem: when to stop a generator-verifier loop whose generator adapts to a cheap, exploitable verifier

  • target: stopped FDR of accepted proposals judged by a hidden expensive oracle
  • guarantee holds up to the κ-th acceptance, under arbitrary within-run dependence
  • Hegazy, Jordan, Dieuleveut method: three parts
  • index-betting e-values per round
    • put the deployment score window among logged null windows, permute, bet with a batch-symmetric strategy
    • validity needs a budgeted symmetric betting rule, not a correct likelihood model
    • fit leave-one-out likelihood-ratio scores
  • online e-BH with an alpha-spending schedule γ_t, controls sup_t FDP ≤ α
  • robust-core conformal risk control for a non-monotone calibration scale
    • finite-grid tree scan computes the core
    • separate splits for e-value construction and calibration evaluation
  • synthetic: 20 reps, 50 rounds, α=0.10, stopped FDP 0.082 (robust-core) and 0.085 (envelope)
  • protein design (RFdiffusion, Proteina): cheap ESMFold score vs hidden AlphaFold 3 oracle
    • success needs 4 thresholds, e.g. motif RMSD ≤ 0.75 Å, pLDDT ≥ 85
    • 300 trajectories x 30 rounds each assumptions
  • exchangeable historical and deployment runs, valid e-values, hidden labels
  • no guarantee under distribution shift Verus relevance (inference)
  • a compile pass is a proxy; wrong specs make it exploitable
    • threat high if Verus acceptance is treated as ground truth
  • needs an independent oracle (spec test) to calibrate
  • statistics stay outside Verus, only deterministic checks are proved

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